From Longman Dictionary of Contemporary English Related topics: Insects louse1 /laʊs/ noun [ countable] 1 (plural lice /laɪs/) a small insect that lives on the hair or skin of people or animals 2 (plural louses) informal someone who is nasty and unpleasant Examples from the Corpus louse • I did comb out a single dead louse, and we inspected it o louse noun [ C ] us / lɑʊs / plural lice us / lɑɪs / Add to word list a small insect that lives on the bodies of people and animals (Definition of louse from the Cambridge Academic Content Dictionary © Cambridge University Press) Examples of louse Britannica.com: Encyclopedia article about lice. Love words? Need even more definitions? Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free! Merriam-Webster unabridged. The meaning of LICE is plural of louse. The plural of "louse" is "lice." Lice spread diseases such as typhus. Lice cannot survive for long if removed from their host. Some words do not form their plurals by adding 's' to the end but by changing their forms (e.g., man becomes men, foot becomes feet, tooth becomes teeth). Are You Good at Plurals? Here's a quick test. plural of cello celles hnoi1.